TitleProduct

Good Quanlity with Low Price Ketoconazole

  • Price:

    Negotiable

  • minimum:

  • Total supply:

  • Delivery term:

    The date of payment from buyers deliver within days

  • seat:

    Shanghai

  • Validity to:

    Long-term effective

  • Last update:

    2017-11-12 06:16

  • Browse the number:

    238

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Lonwin Industry Group Limited
Contactaixin:

Mr. Sparkle(Mr.)  

Email:

telephone:

Arrea:

Shanghai

Address:

Room 407, Building a, No. 966 Huaxu Rd, Qingpu District, Shanghai, China

Website:

http://lonwinchem.ako-pump.com/

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Introduction

Ketoconazole

1.Synonyms: cis-1-Acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine

2.Molecular Formula: C26H28Cl2N4O4

3.Molecular Weight: 531.44

4.CAS: 65277-42-1

5.EINECS: 265-667-4

6.Melting point: 146 ºC

7.Standard: USP33

8.Type: Antibiotic and Antimicrobial Agents

9.Appearance: white or almost white crystalline powder

Ketoconazole is a synthetic antifungal drug used to prevent and treat fungal skin infections, especially in immunocompromised patients such as those with AIDS or those on chemotherapy. Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral tablet.

Function

1. Systemic fungal infections, such as systemic candidiasis, Candida, under spherical spore bacteria disease, histoplasma fungus disease, ball, Bud spore bacteria disease bacteria.

2. By skin fungi and (or) yeast caused of skin, and hair and refers to (toe) of infection (skin fungi disease, and methyl Tinea, and beads bacteria sex methyl week inflammatory, and spotted Tinea, and scalp bran rash Tinea sex hair follicles inflammatory and the chronic skin mucosa beads bacteria disease,), dang local treatment invalid or due to infection parts, and area and the depth, factors cannot medication Shi, available the products treatment.

3. Local treatment of chronic, recurrent vaginal candidiasis.

4. For prophylaxis because of reduced immune function (genetic and caused by disease or drugs) and prone to fungal infections in patients.

Application

This product is an imidazole antifungal drug. For skin fungi, yeasts (Candida, pityrosporum bacteria genus, ball intends to Saccharomyces, Cryptococcus), duplex fungi or Eumycetes bacteriostatic and bactericidal action; apart from the entomophthorales,, the product of the Aspergillus, Shen sporotrichum, some dark Spore, Mucor are lower. The main mechanism for highly selective disturbance of activity of fungal cytochrome P-450, thus inhibiting cell membrane ergosterol biosynthesis in fungi.

This product is an imidazole antifungal drug. For skin fungi, yeasts (Candida, pityrosporum bacteria genus, ball intends to Saccharomyces, Cryptococcus), duplex fungi or Eumycetes bacteriostatic and bactericidal action; apart from the entomophthorales,, the product of the Aspergillus, Shen sporotrichum, some dark Spore, Mucor are lower. The main mechanism for highly selective disturbance of activity of fungal cytochrome P-450, thus inhibiting cell membrane ergosterol biosynthesis in fungi.

Specification

 

Items
Standard 
Results
Characters
white or almost white powder
Qualified
Identification
Meets the requirements
Qualified
Melting range
148°C ~ 152°C
148.0~ 150.0°C
Appearance of solution
Meets the requirements
Qualified
Organic volatile impurities
Meets USP30
Qualified
Specific rotation
-1° ~ +1°(USP30)
 
-0.10° ~ +0.10°(EP5.0,BP2005)
 
Chromatographic purity
Meets the requirements
Qualified
Heavy metals
≤0.002%
Qualified
Loss on drying
≤0.5%
0.001
Residue on ignition
≤0.1%
0.0005
Assay
98.0% ~ 102.0%(USP30)
0.9969
 
99.0%~101.0%(EP5.0,BP2005)
 
CONCLUSION:
This is certify that the product complies to the standards of USP29,EP5.0,BP2005
Packing&Storage
 
 
Packaging Detail
0.5kgs/Al-Bottle
1.0kgs/Al- Bottle
2.0kgs/Al- Bottle
5.0 kgs/Al-Bottle
25.0 kgs/drum
or upon customers' request.
Storage
Store in a well-closed container away from moisture
Shelf Life
2 years if sealed and store away from direct sun light.
Delivery Detail
Within 3 days after get the payment